Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346959 | 0.84 | HTT (0.44) | HTTMEN1KMT2ADPP7KDM4E | |
| SCHEMBL7344617 | 0.82 | HTT (0.44) | HTTMEN1KMT2ADPP7OPRM1 | |
| SCHEMBL7346191 | 0.77 | CALM1 (0.36) | HTTMEN1KMT2ADPP7KDM4E | |
| SCHEMBL7352348 | 0.76 | MEN1 (0.41) | MEN1KMT2AKDM4ESLC6A4ALDH1A1 | |
| SCHEMBL7351902 | 0.76 | HTT (0.41) | HTTMEN1KMT2ADPP7OPRM1 | |
| SCHEMBL7346290 | 0.74 | ADRB2 (0.42) | KDM4ETDP1 | |
| SCHEMBL11237204 | 0.72 | RIPK1 (0.46) | HTTMEN1KMT2ADPP7KDM4E | |
| SCHEMBL14356718 | 0.72 | RIPK1 (0.46) | HTTMEN1KMT2ADPP7KDM4E | |
| SCHEMBL7353234 | 0.72 | HTT (0.46) | HTTDPP7KDM4ESLC6A4ALDH1A1 | |
| SCHEMBL7352468 | 0.71 | HTT (0.44) | HTTMEN1KMT2AKDM4EHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |