Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7242187 | 0.99 | HTT (0.42) | HTTCCR6PAX8ALOX5MAPT | |
| SCHEMBL8029844 | 0.99 | HTT (0.42) | HTTCCR6PAX8ALOX5MAPT | |
| SCHEMBL7359299 | 0.96 | HTT (0.44) | HTTCCR6PAX8ALOX5MAPT | |
| SCHEMBL8039587 | 0.93 | CCR6 (0.42) | HTTCCR6PAX8ALOX5MAPK1 | |
| SCHEMBL989683 | 0.93 | CCR6 (0.45) | CCR6PAX8MAPK1SLC6A3ALDH1A1 | |
| SCHEMBL7355382 | 0.91 | HTT (0.43) | HTTCCR6PAX8MAPK1SLC6A3 | |
| SCHEMBL6661417 | 0.87 | CCR6 (0.41) | CCR6PAX8MAPK1SLC6A3ALDH1A1 | |
| SCHEMBL7358565 | 0.84 | CCR6 (0.39) | CCR6PAX8MAPK1SLC6A3ALDH1A1 | |
| SCHEMBL6827318 | 0.84 | CTSL (0.39) | CCR6PAX8MAPK1SLC6A3ALDH1A1 | |
| SCHEMBL9228435 | 0.84 | ALDH1A1 (0.41) | CCR6PAX8MAPTMAPK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048911-A1 | MONOBACTAM ENZYME INHIBITORS | NAEJA PHARMACEUTICAL INC. (GB) | 1999-09-30 | — | — | WO | disclosed |
| EP-0646573-A1 | Preparation of protected and unprotected guanidino-substituted carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-05 | — | — | EP | disclosed |