Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603401 | 0.82 | LTA4H (0.47) | PDE3BPDE3AP2RY12LTA4HALDH1A1 | |
| SCHEMBL11456703 | 0.78 | L3MBTL1 (0.71) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL810018 | 0.78 | PPARD (0.53) | PDE3BPDE3AP2RY12LTA4HMAPT | |
| SCHEMBL6765132 | 0.78 | LTA4H (0.53) | PDE3BPDE3AP2RY12LTA4HMAPT | |
| SCHEMBL13948678 | 0.78 | L3MBTL1 (0.61) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL4275826 | 0.77 | HDAC1 (0.56) | PDE3BPDE3AP2RY12LTA4HMAPT | |
| SCHEMBL8727471 | 0.77 | HTT (0.49) | PDE3BPDE3AP2RY12LTA4HMAPT | |
| SCHEMBL188550 | 0.76 | MAPT (0.50) | PDE3BPDE3AP2RY12LTA4HMAPT | |
| SCHEMBL15707774 | 0.76 | MAPT (0.63) | LTA4HMAPTALDH1A1LMNAHTT | |
| SCHEMBL6329715 | 0.76 | LTA4H (0.54) | PDE3BPDE3AP2RY12LTA4HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776330-B1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECH NV (AN) | 2003-08-20 | — | — | EP | disclosed |
| EP-0776330-A4 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECH NV (AN) | 1999-07-28 | — | — | EP | disclosed |
| US-5917016-A | USEFUL AS PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5679773-A | SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0776330-A2 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996000378-A1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |