Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362070 | 0.93 | KMT2A (0.52) | KMT2ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7360497 | 0.91 | NPC1 (0.48) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7351784 | 0.89 | KMT2A (0.46) | KMT2ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7354626 | 0.86 | KDM4E (0.43) | KMT2ANPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7361870 | 0.81 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL7353274 | 0.80 | KDM4E (0.42) | KMT2ALMNAMAPTKDM4EHTR1A | |
| SCHEMBL7360192 | 0.79 | KDM4E (0.42) | KMT2ASMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL7355443 | 0.79 | KDM4E (0.42) | KMT2ASMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL5846101 | 0.79 | DRD2 (0.56) | KMT2ASMN1; SMN2LMNAMEN1SIGMAR1 | |
| SCHEMBL7355373 | 0.78 | KDM4E (0.42) | KMT2ASMN1; SMN2LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |