Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353480 | 0.81 | KMT2A (0.60) | SMN1; SMN2KMT2AKDM4ELMNASIGMAR1 | |
| SCHEMBL7386018 | 0.80 | SIGMAR1 (0.42) | KDM4ESIGMAR1MAPTPARP1HTR1A | |
| Dimethylamine SCHEMBL7353096 | 0.80 | PARP1 (0.51) | SIGMAR1PARP1 | |
| Hydrochloric Acid SCHEMBL7357103 | 0.80 | HTR1A (0.47) | KMT2AKDM4ESIGMAR1PARP1HTR1A | |
| SCHEMBL7360005 | 0.80 | HTR1A (0.45) | KDM4ELMNASIGMAR1PARP1HTR1A | |
| Dimethylamine SCHEMBL7352059 | 0.79 | PARP1 (0.50) | SIGMAR1PARP1 | |
| SCHEMBL7354508 | 0.79 | SIGMAR1 (0.42) | SIGMAR1PARP1HTR1A | |
| SCHEMBL7356883 | 0.78 | NR1H4 (0.47) | KMT2AMAPT | |
| SCHEMBL7359345 | 0.78 | HTR1A (0.47) | SIGMAR1PARP1HTR1A | |
| SCHEMBL7424139 | 0.78 | SIGMAR1 (0.42) | SIGMAR1PARP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |