Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356210 | 0.81 | TP53 (0.52) | CCR2NOX4CYP1A2KMT2AMEN1 | |
| SCHEMBL7352345 | 0.81 | CCR2 (0.46) | CCR2SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7361149 | 0.81 | SMN1; SMN2 (0.51) | SRCPRKACAPRKACGPRKACBNOX4 | |
| SCHEMBL7352784 | 0.79 | PGR (0.49) | CCR2SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7361866 | 0.75 | CFTR (0.48) | CCR2NOX4KMT2AMEN1PLA2G2A | |
| SCHEMBL7354439 | 0.73 | CYP1A2 (0.48) | NOX4CYP1A2TDP1KMT2AMEN1 | |
| SCHEMBL3192269 | 0.71 | PPARG (0.54) | CCR2TDP1 | |
| SCHEMBL18180381 | 0.71 | CYP1A2 (0.66) | CCR2CYP1A2POLBMAPT | |
| SCHEMBL30643815 | 0.71 | CYP2C19 (0.64) | CYP1A2TDP1KMT2AMEN1IDO1 | |
| SCHEMBL76204 | 0.71 | CYP2C19 (0.64) | CYP1A2TDP1KMT2AMEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6057304-A | Quinoxaline-phosphonic acid derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |