Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 3/20 | 0.66 |
| ▸ | CPA1 | P15085 | 2/20 | 0.66 |
| ▸ | CPB1 | P15086 | 1/20 | 0.66 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399603 | 1.00 | CPA3 (0.66) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL7289839 | 1.00 | CPA3 (0.66) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL3701204 | 0.92 | CPA1 (0.57) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL2571746 | 0.91 | CPA1 (0.56) | CPA3CPA1CPB1CPB2ALDH1A1 | |
| SCHEMBL7346272 | 0.91 | CPA1 (0.55) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL7346268 | 0.91 | CPA1 (0.55) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL21811160 | 0.87 | CYP1A2 (0.59) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL7320025 | 0.87 | ALDH1A1 (0.56) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL7320029 | 0.87 | ALDH1A1 (0.56) | CPA3CPA1CPB1CPB2CYP1A2 | |
| SCHEMBL28639320 | 0.86 | CPA1 (0.51) | CPA3CPA1CPB1CPB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869518-A | USEFUL IN THE TREATMENT OF OBESITY AND HYPERGLYCEMIA | SYNTHELABO (FR) | 1999-02-09 | — | — | US | disclosed |
| US-5712417-A | Inhibitors of retroviral proteases | ABBOTT LABORATORIES (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5442044-A | Hypotensive agents | PFIZER INC. (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0661292-A1 | Orally active renin inhibitors | PFIZER INC. (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| EP-0438233-A2 | Orally active renin inhibitors | PFIZER INC. (US) | 1991-07-24 | — | — | EP | disclosed |