Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735186 | 0.82 | RAB9A (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL734100 | 0.77 | OPRM1 (0.40) | OPRM1OPRK1OPRL1 | |
| SCHEMBL733287 | 0.76 | TMEM97 (0.45) | CCNB2CDK1CCNB1CCNB3OPRM1 | |
| SCHEMBL3930943 | 0.74 | DYRK1A (0.42) | CCNB2CDK1CCNB1CCNB3OPRM1 | |
| SCHEMBL734179 | 0.72 | OPRM1 (0.37) | OPRM1OPRL1 | |
| SCHEMBL2085349 | 0.70 | RIPK1 (0.50) | RIPK1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL735024 | 0.68 | OPRM1 (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL734668 | 0.67 | OPRM1 (0.45) | OPRM1OPRK1OPRL1 | |
| SCHEMBL734275 | 0.67 | OPRM1 (0.39) | OPRM1OPRK1OPRL1 | |
| SCHEMBL734169 | 0.66 | OPRM1 (0.57) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138187-B2 | Substituted heteroaryl derivatives | GRUENENTHAL GMBH (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | GRUNENTHAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009986-A1 | SUBSTITUTED HETEROARYL DERIVATIVES | CYP3A43, HMGCR, ABCG2 | RIPK1 4392/4885CCNB2 1406/4885CDK1 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.