Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354033 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7352921 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7354534 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7348253 | 0.77 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL7388152 | 0.77 | ITGB3 (0.56) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7354037 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7354459 | 0.75 | ITGB3 (0.48) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7721971 | 0.72 | ITGB3 (0.58) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL13583552 | 0.71 | SMN1; SMN2 (0.52) | KMT2AHDAC6HDAC1 | |
| SCHEMBL8971449 | 0.71 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | claimed |
| US-5543425-A | ANTIAGGLOMERANTS | G. D. SEARLE & CO. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5409939-A | Phenyl amidine thio derivatives useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994018162-A1 | PHENYL AMIDINE THIO DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-08-18 | — | — | WO | disclosed |