Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357765 | 0.80 | KDR (0.35) | CUL4AKDM4EALDH1A1 | |
| SCHEMBL7351971 | 0.80 | MAPT (0.34) | CUL4AKDM4EALDH1A1 | |
| SCHEMBL7349447 | 0.76 | GABRA1 (0.36) | PARP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7354835 | 0.68 | CUL4A (0.36) | CUL4APARP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11126620 | 0.59 | MEN1 (0.48) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19942689 | 0.58 | MEN1 (0.34) | — | |
| SCHEMBL15101419 | 0.57 | GFER (0.46) | CUL4APARP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4793090 | 0.54 | SMN1; SMN2 (0.53) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23161511 | 0.52 | SMN1; SMN2 (0.56) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3042980 | 0.52 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5367077-A | Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands | NEUROGEN CORPORATION (US) | 1994-11-22 | — | — | US | claimed |
| WO-1994025461-A1 | CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1994-11-10 | — | — | WO | claimed |
| US-5367077-A | Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands | NEUROGEN CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1994025461-A1 | CERTAIN CYCLOALKYL AND AZACYCLOALKYL PYRROLOPYRIDINES; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |