Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | PTPRC | P08575 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211937 | 0.94 | MAOA (0.49) | MAOAMAOBCDC25BCDC25AKMT2A | |
| SCHEMBL503745 | 0.85 | MAOA (0.50) | MAOAMAOBKMT2ALMNAPTPRC | |
| SCHEMBL30895284 | 0.85 | MAOA (0.50) | MAOAMAOBKMT2ALMNAPTPRC | |
| Hydrochloric Acid SCHEMBL26614007 | 0.83 | MAOA (0.48) | MAOAMAOBKMT2ALMNAPTPRC | |
| SCHEMBL8102488 | 0.82 | CDC25B (0.43) | MAOAMAOBCDC25BCDC25AKMT2A | |
| SCHEMBL30645249 | 0.82 | CDC25B (0.47) | MAOAMAOBCDC25BCDC25AKMT2A | |
| Ethylene SCHEMBL28442445 | 0.81 | MAOA (0.47) | MAOAMAOBKMT2ALMNAPTPRC | |
| SCHEMBL20843280 | 0.81 | MAOA (0.41) | MAOAMAOBCDC25BCDC25AKMT2A | |
| SCHEMBL1243588 | 0.79 | BACE1 (0.52) | MAOAMAOBCDC25BCDC25AKMT2A | |
| SCHEMBL30172862 | 0.79 | BACE1 (0.52) | MAOAMAOBCDC25BCDC25AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015231-B1 | INDENONCARBOXYLIC ACIDS, THEIR ESTERS AND PROCESS FOR THE MANUFACTURE THEREOF | CIBA-GEIGY AG (CH) | 1982-09-01 | — | — | EP | claimed |
| US-4323701-A | FROM DIHALOGENOMALEIC ANHYDRIDES OR ACYL HALIDE AND AN AROMATIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | claimed |
| CN-105521826-B | A kind of Zr catalyst and its prepare chiral alpha-hydroxy-beta -one ester compound method | 大连理工大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-108997306-A | A kind of method that industrialized production prepares fluorine substituted diphenylamine bithiophene S, S- dioxide | 浙江九洲药物科技有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-1738795-A | Indanone carboxylic acid derivatives and their use in the treatment and prevention of diabetes and dyslipidemia | MERCK PATENT GMBH (DE) | 2006-02-22 | — | — | CN | disclosed |
| CN-1129428-C | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2003-12-03 | — | — | CN | disclosed |
| CN-1034569-C | ET (ENDOTHELIN) receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1997-04-16 | — | — | CN | disclosed |
| CN-1145223-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1997-03-19 | — | — | CN | disclosed |
| CN-1124923-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1996-06-19 | — | — | CN | disclosed |
| EP-0699069-A4 | — | — | 1996-04-03 | — | — | EP | disclosed |
| EP-0699069-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994025013-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-10 | — | — | WO | disclosed |
| CN-1073161-A | ET (ENDOTHELIN) receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-06-16 | — | — | CN | disclosed |
| US-4463142-A | Photocrosslinkable polymers with side groups derived from indenone and the preparation and use of these polymers | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4399259-A | ACRYLIC ESTER HOMO- AND COPOLYMERS; KETONE RESINS; BROMO- AND CHLOROPOLYMERS; PHOTORESISTS | CIBA-GEIGY CORPORATION (US) | 1983-08-16 | — | — | US | disclosed |
| US-4323701-A | FROM DIHALOGENOMALEIC ANHYDRIDES OR ACYL HALIDE AND AN AROMATIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| US-4323701-A | FROM DIHALOGENOMALEIC ANHYDRIDES OR ACYL HALIDE AND AN AROMATIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0015231-A1 | Indenoncarboxylic acids, their esters and process for the manufacture thereof | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |
| EP-0015231-A1 | Indenoncarboxylic acids, their esters and process for the manufacture thereof | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |