Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | CTSE | P14091 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355092 | 1.00 | REN (0.54) | RENCTSDCTSE | |
| SCHEMBL7346471 | 0.99 | REN (0.54) | RENCTSDCTSE | |
| SCHEMBL7346458 | 0.99 | REN (0.54) | RENCTSDCTSE | |
| SCHEMBL7272241 | 0.88 | REN (0.58) | REN | |
| SCHEMBL5709645 | 0.88 | REN (0.58) | REN | |
| SCHEMBL6696371 | 0.88 | REN (0.58) | REN | |
| SCHEMBL7266599 | 0.88 | REN (0.58) | REN | |
| SCHEMBL7357035 | 0.86 | REN (0.49) | RENCTSDCTSE | |
| SCHEMBL7350020 | 0.85 | REN (0.61) | REN | |
| SCHEMBL7349332 | 0.85 | REN (0.66) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338726-A | Hypotensive agents, antiulcer agents | ABBOTT LABORATORIES (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | disclosed |