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Sugi Predict / Compounds / SCHEMBL7357035

SCHEMBL7357035

SCHEMBL7357035

CC[C@H](C)[C@H](NC(=O)[C@H](C)N(C(=O)OC(C)(C)C)C1CCCCC1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)CC(C)C

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 14/20 0.49
▸ CTSD P07339 1/20 0.45
▸ CTSE P14091 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7346458 0.87 REN (0.54) RENCTSDCTSE
SCHEMBL7346471 0.87 REN (0.54) RENCTSDCTSE
SCHEMBL7355086 0.86 REN (0.54) RENCTSDCTSE
SCHEMBL7355092 0.86 REN (0.54) RENCTSDCTSE
SCHEMBL7349106 0.84 REN (0.47) RENCTSDCTSE
SCHEMBL7351762 0.82 REN (0.47) RENCTSDCTSE
SCHEMBL7358156 0.82 REN (0.61) RENCTSDCTSE
SCHEMBL7349332 0.81 REN (0.66) REN
SCHEMBL7349316 0.81 REN (0.66) REN
SCHEMBL7351430 0.80 REN (0.43) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338726-A Hypotensive agents, antiulcer agents ABBOTT LABORATORIES (US) 1994-08-16 — — US disclosed
EP-0569487-A4 — — 1994-04-27 — — EP disclosed
EP-0569487-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1993-11-18 — — EP disclosed
WO-1992013545-A1 ENDOTHELIN CONVERTING ENZYME INHIBITORS ABBOTT LABORATORIES (US) 1992-08-20 — — WO disclosed