Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349316 | 1.00 | REN (0.66) | REN | |
| SCHEMBL7346458 | 0.86 | REN (0.54) | REN | |
| SCHEMBL7346471 | 0.86 | REN (0.54) | REN | |
| SCHEMBL7355092 | 0.85 | REN (0.54) | REN | |
| SCHEMBL7355086 | 0.85 | REN (0.54) | REN | |
| SCHEMBL7357035 | 0.81 | REN (0.49) | REN | |
| SCHEMBL7357022 | 0.79 | REN (0.47) | REN | |
| SCHEMBL7344132 | 0.78 | REN (0.65) | REN | |
| SCHEMBL29429781 | 0.77 | CPB2 (0.49) | REN | |
| SCHEMBL7280141 | 0.76 | REN (0.60) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338726-A | Hypotensive agents, antiulcer agents | ABBOTT LABORATORIES (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0569487-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0569487-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | disclosed |