Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.47 |
| ▸ | FCER2 | P06734 | 5/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355276 | 0.89 | BRS3 (0.47) | MMP1FCER2ANPEPBRS3MEN1 | |
| SCHEMBL7359233 | 0.89 | BRS3 (0.51) | MMP1BRS3KMT2AITGB1ITGA4 | |
| SCHEMBL7362211 | 0.87 | MCHR1 (0.47) | MMP1FCER2ANPEPMEN1KMT2A | |
| SCHEMBL7360073 | 0.86 | KLKB1 (0.47) | MMP1ITGB1ITGA4PTPN1PTPN2 | |
| SCHEMBL7353133 | 0.85 | FCER2 (0.57) | MMP1FCER2ANPEPMMP8 | |
| SCHEMBL7353158 | 0.83 | FCER2 (0.57) | MMP1FCER2MMP8 | |
| SCHEMBL8309375 | 0.83 | PSMB1 (0.52) | BRS3MEN1KMT2A | |
| SCHEMBL7358942 | 0.82 | KMT2A (0.53) | BRS3MEN1KMT2AMMP8 | |
| SCHEMBL7361514 | 0.81 | BACE1 (0.48) | MMP1FCER2MEN1KMT2AMMP8 | |
| SCHEMBL7354151 | 0.81 | CTSL (0.46) | MMP1FCER2ANPEPMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |