Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 10/20 | 0.46 |
| ▸ | METAP1 | P53582 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356020 | 0.89 | METAP2 (0.46) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7353742 | 0.84 | METAP2 (0.47) | METAP2METAP1CTSS | |
| SCHEMBL7353713 | 0.84 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL7355544 | 0.77 | METAP2 (0.58) | METAP2METAP1 | |
| SCHEMBL6484036 | 0.76 | METAP2 (0.64) | METAP2METAP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7360924 | 0.76 | METAP2 (0.49) | METAP2METAP1CTSSEPHX1 | |
| Hydrochloric Acid SCHEMBL7356207 | 0.76 | METAP2 (0.57) | METAP2METAP1 | |
| SCHEMBL7352302 | 0.75 | METAP2 (0.60) | METAP2METAP1CTSS | |
| SCHEMBL16730492 | 0.74 | METAP2 (0.51) | METAP2METAP1ALDH1A1EPHX1 | |
| SCHEMBL7353581 | 0.73 | METAP2 (0.54) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |