Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 10/20 | 0.49 |
| ▸ | METAP1 | P53582 | 6/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353713 | 0.82 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL7356020 | 0.82 | METAP2 (0.46) | METAP2METAP1EPHX1CTSS | |
| SCHEMBL7360474 | 0.82 | METAP2 (0.66) | METAP2METAP1EPHX1CTSDSCN9A | |
| Hydrochloric Acid SCHEMBL7352224 | 0.81 | METAP2 (0.64) | METAP2METAP1EPHX1CTSDSCN9A | |
| SCHEMBL7353742 | 0.79 | METAP2 (0.47) | METAP2METAP1CTSLCTSSCTSK | |
| SCHEMBL7356284 | 0.78 | METAP2 (0.61) | METAP2METAP1 | |
| SCHEMBL6480057 | 0.78 | METAP2 (0.69) | METAP2METAP1EPHX1CTSD | |
| Hydrochloric Acid SCHEMBL7350513 | 0.77 | METAP2 (0.60) | METAP2METAP1 | |
| SCHEMBL7355571 | 0.76 | METAP2 (0.46) | METAP2METAP1EPHX1CTSS | |
| SCHEMBL7355544 | 0.73 | METAP2 (0.58) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |