Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348929 | 1.00 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL7348925 | 1.00 | SLC6A3 (0.61) | SLC6A3SIGMAR1ACHEDRD2DRD3 | |
| SCHEMBL8879791 | 0.86 | L3MBTL1 (0.50) | SLC6A3SIGMAR1 | |
| SCHEMBL4815665 | 0.85 | CYP2D6 (0.68) | SIGMAR1ACHE | |
| SCHEMBL7354339 | 0.84 | HTR2A (0.51) | SLC6A3 | |
| SCHEMBL7354346 | 0.84 | HTR2A (0.51) | SLC6A3 | |
| SCHEMBL14279291 | 0.83 | HRH3 (0.56) | — | |
| SCHEMBL4814084 | 0.82 | L3MBTL3 (0.58) | SIGMAR1 | |
| SCHEMBL4814066 | 0.82 | L3MBTL3 (0.58) | SIGMAR1 | |
| SCHEMBL6795832 | 0.81 | L3MBTL1 (0.51) | SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889043-B1 | 5,11-DIHYDRODIBENZ b,e] 1,4]OXAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAING THE DERIVATIVES | AJINOMOTO KK (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6127361-A | FOR TREATMENT OR PREVENTION OF GASTROINTESTINAL MOVING FUNCTION DISORDERS, IRRITABLE BOWEL SYNDROME | AJINOMO CO., INC. (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0889043-A1 | 5,11-DIHYDRODIBENZ b,e] 1,4]OXAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAING THE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 1999-01-07 | — | — | EP | disclosed |