Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982524 | 0.81 | TSHR (0.46) | SMN1; SMN2RECQLMAPK10TSHRHSD17B10 | |
| SCHEMBL7360918 | 0.81 | CNR1 (0.43) | SMN1; SMN2TSHRHSD17B10KDM4ETBXAS1 | |
| SCHEMBL7353327 | 0.76 | NPC1 (0.42) | SMN1; SMN2RECQLMAPK10TBXAS1POLB | |
| SCHEMBL8267186 | 0.75 | LMNA (0.39) | SMN1; SMN2TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL13668154 | 0.74 | LMNA (0.39) | SMN1; SMN2TSHRKDM4EPOLBALDH1A1 | |
| SCHEMBL3042449 | 0.74 | LMNA (0.43) | TSHRHSD17B10KDM4EADORA2BKMT2A | |
| SCHEMBL12894985 | 0.73 | NR4A2 (0.46) | TSHRKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL4974937 | 0.71 | ALDH1A1 (0.54) | SMN1; SMN2TSHRHSD17B10KDM4EPOLB | |
| SCHEMBL987310 | 0.71 | NPC1 (0.44) | SMN1; SMN2RECQLTSHRHSD17B10KDM4E | |
| SCHEMBL21125120 | 0.70 | TSHR (0.47) | SMN1; SMN2MAPK10TSHRHSD17B10TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |