Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361829 | 0.85 | MAPT (0.38) | TSHRKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7355990 | 0.82 | EGLN3 (0.40) | TSHRKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4908687 | 0.81 | TSHR (0.41) | TSHRKDM4ETBXAS1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7357414 | 0.81 | PRPS1 (0.38) | CNR1TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7355840 | 0.81 | SMN1; SMN2 (0.44) | CNR1TSHRKDM4ETBXAS1ALDH1A1 | |
| SCHEMBL12226875 | 0.81 | TSHR (0.51) | TSHRKDM4ETBXAS1ALDH1A1HSD17B10 | |
| SCHEMBL7353986 | 0.81 | KDM4E (0.36) | CNR1KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7386018 | 0.78 | SIGMAR1 (0.42) | KDM4EALDH1A1MAPT | |
| SCHEMBL7359893 | 0.77 | KMT2A (0.43) | CNR1TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7356719 | 0.76 | HPGD (0.44) | TSHRKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |