Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7357414 | 0.88 | PRPS1 (0.38) | EGLN3EGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13668135 | 0.85 | EGLN3 (0.38) | EGLN3EGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13668134 | 0.84 | EGLN3 (0.37) | EGLN3EGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7353986 | 0.84 | KDM4E (0.36) | EGLN3EGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13943658 | 0.84 | EGLN3 (0.37) | EGLN3EGLN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7355082 | 0.84 | EGLN1 (0.45) | EGLN1LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7356719 | 0.82 | HPGD (0.44) | SMN1; SMN2ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL7361829 | 0.81 | MAPT (0.38) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL7358428 | 0.81 | EGLN1 (0.40) | EGLN1LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7359893 | 0.80 | KMT2A (0.43) | LMNAALDH1A1KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |