Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360918 | 0.85 | CNR1 (0.43) | MAPTKDM4ENPSR1POLBSMN1; SMN2 | |
| SCHEMBL7355990 | 0.81 | EGLN3 (0.40) | MAPTKDM4ESMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL7357414 | 0.80 | PRPS1 (0.38) | MAPTKDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL7353986 | 0.80 | KDM4E (0.36) | MAPTKDM4ESMN1; SMN2LMNAHTT | |
| SCHEMBL7424139 | 0.79 | SIGMAR1 (0.42) | — | |
| SCHEMBL7355082 | 0.77 | EGLN1 (0.45) | MAPTKDM4EPOLBSMN1; SMN2LMNA | |
| SCHEMBL7359893 | 0.76 | KMT2A (0.43) | MAPTKDM4EPOLBL3MBTL1LMNA | |
| SCHEMBL7356719 | 0.75 | HPGD (0.44) | MAPTKDM4EPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7358428 | 0.74 | EGLN1 (0.40) | KDM4ENPSR1NPC1SMN1; SMN2LMNA | |
| SCHEMBL13668133 | 0.74 | TSHR (0.39) | MAPTKDM4ENPSR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |