Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MTTP | P55157 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355082 | 0.86 | EGLN1 (0.45) | EGLN1RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL7357340 | 0.84 | SMN1; SMN2 (0.45) | RAB9AALDH1A1LMNANPC1KDM4E | |
| SCHEMBL7356630 | 0.84 | CHRNB2 (0.46) | EGLN1RAB9ALMNANPC1CNR1 | |
| SCHEMBL7354930 | 0.84 | NPC1 (0.52) | RAB9AALDH1A1LMNANPC1NPSR1 | |
| SCHEMBL7355990 | 0.81 | EGLN3 (0.40) | EGLN1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7360967 | 0.81 | TSHR (0.46) | RAB9AALDH1A1LMNANPC1KDM4E | |
| Hydrochloric Acid SCHEMBL7357414 | 0.80 | PRPS1 (0.38) | EGLN1ALDH1A1LMNAKDM4ECNR1 | |
| SCHEMBL7356668 | 0.80 | ALDH1A1 (0.48) | RAB9AALDH1A1LMNANPC1KDM4E | |
| SCHEMBL7360005 | 0.79 | HTR1A (0.45) | LMNAKDM4E | |
| SCHEMBL7353986 | 0.77 | KDM4E (0.36) | EGLN1ALDH1A1LMNAKDM4ECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |