Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 9/20 | 0.62 |
| ▸ | HTR7 | P34969 | 8/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL1545387 | 0.92 | HTR2A (0.60) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| Fumaric Acid SCHEMBL1545384 | 0.92 | HTR2A (0.60) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8346979 | 0.86 | DRD2 (0.69) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545404 | 0.86 | DRD2 (0.66) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL9394136 | 0.84 | DRD2 (0.64) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545195 | 0.83 | ACHE (0.80) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL18432239 | 0.83 | DRD2 (0.82) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545719 | 0.83 | DRD2 (0.74) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545611 | 0.82 | ACHE (0.93) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1544799 | 0.81 | ACHE (0.77) | DRD2SLC6A4ACHEHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612318-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-08-31 | — | — | EP | claimed |
| EP-0542136-A1 | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-05-19 | — | — | EP | claimed |
| WO-1993009102-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1993-05-13 | — | — | WO | claimed |