Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 7/20 | 0.59 |
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346979 | 0.85 | DRD2 (0.69) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545404 | 0.85 | DRD2 (0.66) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL7356121 | 0.84 | DRD2 (0.67) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545719 | 0.82 | DRD2 (0.74) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL10638265 | 0.82 | ACHE (0.71) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| Fumaric Acid SCHEMBL8350185 | 0.81 | HTR2A (0.61) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL10638364 | 0.81 | ACHE (0.69) | DRD2SLC6A4ACHEHTR2ADRD3 | |
| SCHEMBL7353484 | 0.80 | ACHE (0.76) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL18432239 | 0.80 | DRD2 (0.82) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545611 | 0.80 | ACHE (0.93) | DRD2SLC6A4ACHEHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027992-A1 | PIPERIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-12-08 | — | — | WO | disclosed |