Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870373 | 0.86 | BRD4 (0.61) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL1737254 | 0.86 | BRD4 (0.61) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL14840493 | 0.83 | TSHR (0.58) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL7356194 | 0.83 | ALDH1A1 (0.61) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL14840457 | 0.81 | TSHR (0.54) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL2801546 | 0.81 | BRD4 (0.56) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL7348096 | 0.80 | TSHR (0.58) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL21639387 | 0.79 | TSHR (0.53) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL12897074 | 0.78 | TSHR (0.59) | TSHRBRD4HSD17B10HTTALDH1A1 | |
| SCHEMBL29571304 | 0.78 | TSHR (0.63) | TSHRBRD4HSD17B10HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851546-A | Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-12-22 | — | — | US | disclosed |