Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175816 | 0.86 | ALDH1A1 (0.45) | HTTALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL7621765 | 0.82 | ALDH1A1 (0.53) | HTTALDH1A1CCR6PAX8MAPK1 | |
| Phosphoric Acid SCHEMBL11428997 | 0.81 | CCR6 (0.42) | LTA4HCCR6PAX8 | |
| SCHEMBL11414742 | 0.81 | CCR6 (0.39) | LTA4HHTTALDH1A1CCR6PAX8 | |
| SCHEMBL7356270 | 0.80 | CCR6 (0.43) | LTA4HALDH1A1CCR6PAX8 | |
| SCHEMBL29875737 | 0.77 | CCR6 (0.56) | HTTALDH1A1CCR6PAX8MAPK1 | |
| SCHEMBL3372744 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CCR6PAX8MAPK1L3MBTL1 | |
| SCHEMBL9489302 | 0.76 | CTSL (0.55) | HTTALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL1240675 | 0.75 | ALDH1A1 (0.59) | LTA4HHTTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL6741068 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CCR6PAX8MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786462-B1 | DC107 derivatives | KYOWA HAKKO KOGYO KK (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5733924-A | BACTERICIDES AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0786462-A1 | DC107 DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |