Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 2/20 | 0.30 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836726 | 0.90 | KMT2A (0.35) | KMT2AHPGDTSHRPDE9ARAD51 | |
| SCHEMBL7356637 | 0.75 | PDE2A (0.40) | KMT2ATSHRPDE9A | |
| SCHEMBL7356548 | 0.73 | PDE2A (0.40) | KMT2A | |
| SCHEMBL2833418 | 0.72 | KMT2A (0.40) | KMT2AHPGDTSHRRAD51 | |
| SCHEMBL7355183 | 0.70 | PDE2A (0.48) | KMT2A | |
| SCHEMBL7354927 | 0.70 | PDE2A (0.57) | HPGD | |
| SCHEMBL1961181 | 0.69 | ALDH1A1 (0.42) | KMT2AHPGD | |
| SCHEMBL2831825 | 0.66 | PDE2A (0.46) | KMT2AHPGDPDE9ARAD51 | |
| SCHEMBL6991684 | 0.65 | PDE9A (0.46) | PDE9A | |
| SCHEMBL1961857 | 0.65 | HPGD (0.42) | KMT2AHPGDTSHRRAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107968-B1 | DIHYDRO-[1,2,3]TRIAZOLO-[4,5-D]PYRIMIDIN-7-ONE | BAYER AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| US-6458796-B1 | METHOD OF TREATING CARDIOVASCULAR DISORDERS, THROMBOEMBOLIC DISORDERS AND ISCHAEMIAS, AND UROGENITAL SYSTEM DISORDERS, COMPRISING ADMINISTERING TO MAMMALS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |