SCHEMBL73574

SCHEMBL73574

CCOC(=O)c1ccc2nc(N)sc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.65
NPC1 O15118 9/20 0.65
SMN1; SMN2 Q16637 8/20 0.65
STAT1 P42224 1/20 0.65
ALDH1A1 P00352 5/20 0.61
MAPT P10636 4/20 0.61
KDM4E B2RXH2 3/20 0.61
HPGD P15428 2/20 0.61
ALPL P05186 1/20 0.61
GAA P10253 1/20 0.61
CYP2C9 P11712 2/20 0.57
CYP3A4 P08684 4/20 0.56
TP53 P04637 3/20 0.56
HSD17B10 Q99714 3/20 0.56
TSHR P16473 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
LCK P06239 1/20 0.55
USP2 O75604 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9722853 0.89 NPC1 (0.57) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL5208143 0.89 NPC1 (0.52) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
Bromide SCHEMBL261012 0.88 NPC1 (0.51) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL9722808 0.87 NPC1 (0.55) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL4667327 0.86 NPC1 (0.68) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL11439414 0.85 CYP2C9 (0.54) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL9722788 0.85 CYP2C9 (0.60) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL9722767 0.85 CYP2C9 (0.53) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL145671 0.84 NPC1 (0.67) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1
SCHEMBL30189826 0.84 NPC1 (0.67) RAB9ANPC1SMN1; SMN2STAT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655225-B2 Antimycobacterial heterocyclic amides CRESTONE, INC. (US) 2023-05-23 US claimed
CN-112423746-A Novel anti-mycobacterial heterocyclic amides 克莱斯通公司 2021-02-26 CN claimed
US-20210002239-A1 Novel Antimycobacterial Heterocyclic Amides CRESTONE, INC. 2021-01-07 US claimed
EP-3758697-A1 NOVEL ANTIMYCOBACTERIAL HETEROCYCLIC AMIDES Crestone, Inc. (US) 2021-01-06 EP claimed
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-11-20 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-09-02 US disclosed
EP-4547671-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-24 US disclosed
CN-117126578-B Organosilicon polymer/POSS hybrid antifouling coating grafted with antibacterial molecules and preparation method thereof 中国科学院海洋研究所 2025-04-22 CN disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed
US-3954398-A Polyester fibers dyed with a disazo disperse dyestuff CIBA-GEIGY AG (CH) 1976-05-04 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3933786-A Heterocyclic-azo-phenyl compounds containing a styrl group CIBA-GEIGY AG (CH) 1976-01-20 US disclosed
US-3931145-A POLYESTER GAF CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129100-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 RAB9A 2519/4885NPC1 2376/4885SMN1; SMN2 3226/4885
US-20250353862-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 RAB9A 2519/4885NPC1 2376/4885SMN1; SMN2 3226/4885
US-11655225-B2 Antimycobacterial heterocyclic amides AADAC, CPS1, NAT1 RAB9A 1973/4885NPC1 1093/4885SMN1; SMN2 4466/4885
US-12404283-B2 c-MYC mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 RAB9A 2519/4885NPC1 2376/4885SMN1; SMN2 3226/4885
US-20210002239-A1 Novel Antimycobacterial Heterocyclic Amides AADAC, CPS1, ACAT1 RAB9A 1886/4885NPC1 1474/4885SMN1; SMN2 4672/4885
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL RAB9A 3850/4885NPC1 930/4885SMN1; SMN2 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.