Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722853 | 0.92 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9722769 | 0.89 | CYP2C9 (0.57) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9722789 | 0.89 | CYP2C9 (0.51) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL73574 | 0.87 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9722788 | 0.86 | CYP2C9 (0.60) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11439414 | 0.86 | CYP2C9 (0.54) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9722767 | 0.86 | CYP2C9 (0.53) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11833323 | 0.84 | PHLPP2 (0.56) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL14360991 | 0.83 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9722781 | 0.80 | CYP2C9 (0.53) | NPC1RAB9ASMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4118384-A | DIAZOTIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |