Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 4/20 | 0.42 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357536 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7348881 | 0.88 | TUBB4A (0.42) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7348886 | 0.88 | TUBB4A (0.42) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7349224 | 0.88 | F7 (0.46) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7349221 | 0.88 | F7 (0.46) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7359628 | 0.85 | PDE4A (0.47) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL7349929 | 0.85 | PELI1 (0.43) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7349935 | 0.85 | PELI1 (0.43) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7347487 | 0.82 | PDE4A (0.43) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| SCHEMBL7347491 | 0.82 | PDE4A (0.43) | ALDH1A1LMNAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| US-5877190-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-02 | — | — | US | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |