Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145951 | 0.88 | PTGS1 (0.54) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL27828213 | 0.87 | ACHE (0.49) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL4374428 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL12129513 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL28988616 | 0.84 | ACHE (0.46) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL1993610 | 0.84 | AKR1C3 (0.66) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL1760202 | 0.84 | AKR1C3 (0.66) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL4943386 | 0.83 | PTGS2 (0.50) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL602096 | 0.82 | PTGS2 (0.69) | PTGS1PTGS2MAPTCXCR1CXCR2 | |
| SCHEMBL23972306 | 0.82 | LMNA (0.53) | LMNAMAPK1ACHERXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166314-B | Modified conjugated diene polymer and rubber composition containing the same | 株式会社LG化学 | 2023-08-01 | — | — | CN | disclosed |
| CN-113166315-B | Process for producing modified conjugated diene polymer | 株式会社LG化学 | 2023-08-01 | — | — | CN | disclosed |
| CN-109721701-A | A kind of thermoplastic urethane elastomer composition and preparation method and purposes | 万华化学集团股份有限公司 | 2019-05-07 | — | — | CN | disclosed |
| WO-2015076353-A1 | 3-ALKYLPYRAZOLOPYRIDINE DERIVATIVE | 第一三共株式会社 | 2015-05-28 | — | — | WO | disclosed |
| CN-101787188-B | Flame-retardant PC/HIPS composite material and preparation method thereof | POLYMER SCI SHENZHEN NEW MAT | 2012-05-23 | — | — | CN | disclosed |
| US-5338726-A | Hypotensive agents, antiulcer agents | ABBOTT LABORATORIES (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0569487-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0569487-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | disclosed |