Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 7/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 10/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353642 | 0.95 | CHIT1 (0.37) | CHIT1CHIAKCNH2CACNA1B | |
| SCHEMBL7354253 | 0.92 | CACNA1B (0.43) | KCNH2CACNA1BSIGMAR1 | |
| SCHEMBL7359757 | 0.91 | MCHR1 (0.35) | CHIT1CHIAKCNH2CACNA1BSIGMAR1 | |
| SCHEMBL7349808 | 0.91 | CACNA1B (0.38) | CACNA1B | |
| SCHEMBL7359587 | 0.91 | CACNA1B (0.46) | CACNA1BSIGMAR1 | |
| SCHEMBL7349884 | 0.88 | CACNA1B (0.42) | CACNA1B | |
| SCHEMBL7350644 | 0.87 | CACNA1B (0.40) | CACNA1B | |
| SCHEMBL7351806 | 0.86 | CACNA1B (0.45) | CHIT1CHIAKCNH2CACNA1BSIGMAR1 | |
| SCHEMBL7037884 | 0.85 | CACNA1B (0.41) | CHIT1CHIAKCNH2CACNA1B | |
| SCHEMBL7037890 | 0.85 | CACNA1B (0.41) | CHIT1CHIAKCNH2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007689-A1 | ANILINE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |