Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976264 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL30051464 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL9272265 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL4891798 | 0.91 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL561849 | 0.91 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL6444839 | 0.91 | ALDH1A1 (0.58) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| Hydrochloric Acid SCHEMBL4862500 | 0.90 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL8667829 | 0.88 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL27559596 | 0.86 | ALDH1A1 (0.60) | ALDH1A1GAAMAPTHDAC8KDM4C | |
| SCHEMBL6445106 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTHDAC8KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2008-01-24 | — | — | US | disclosed |
| US-7193065-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| EP-1005448-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | Du Pont Pharmaceuticals Company (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999009000-A2 | NOVEL INHIBITORS OF AGGRECANASE AND MATRIX METALLOPROTEINASES FOR THE TREATMENT OF ARTHRITIS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1992020344-A1 | ANTIVIRAL COMBINATIONS CONTAINING NUCLEOSIDE ANALOGS | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | ALDH1A1 547/4885GAA 394/4885MAPT 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.