Sugi Predict

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Lithium

Lithium

SCHEMBL7357936

CC(C)C[C@@](C(N)=O)(C(=O)O)N(C)CCN(C)C.[Li]

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GRM2 Q14416 1/20 0.30
▸ GRM3 Q14832 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7357927 0.97 GRM2 (0.30) GRM2GRM3
SCHEMBL11051641 0.69 MAPT (0.40) —
SCHEMBL27587659 0.63 GRM2 (0.39) GRM2GRM3
SCHEMBL11378903 0.60 GRM2 (0.33) GRM2GRM3
SCHEMBL16892927 0.59 CA2 (0.36) GRM2GRM3
Trifluoroacetic Acid SCHEMBL6890645 0.59 GRM2 (0.36) GRM2GRM3
SCHEMBL3718753 0.58 MMP8 (0.34) GRM2GRM3
SCHEMBL21821202 0.58 GRM2 (0.46) GRM2GRM3
SCHEMBL497762 0.58 GRM2 (0.46) GRM2GRM3
SCHEMBL4659753 0.58 MMP8 (0.34) GRM2GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415981-A4 RETROVIRAL PROTEASE INHIBITORS — 1991-10-09 — — EP disclosed
EP-0415981-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1991-03-13 — — EP disclosed
WO-1989010752-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1989-11-16 — — WO disclosed