Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393944 | 0.85 | GPR119 (0.41) | HRH3GPR119KDM4EPKMTP53 | |
| SCHEMBL7389941 | 0.85 | S1PR1 (0.43) | GPR119KDM4EPKMTP53LMNA | |
| SCHEMBL7389887 | 0.84 | HRH3 (0.41) | HRH3GPR119KDM4EPKMTP53 | |
| SCHEMBL7391404 | 0.83 | GPR119 (0.41) | GPR119KDM4EPKMTP53LMNA | |
| SCHEMBL7484914 | 0.83 | GPR119 (0.42) | HRH3GPR119KDM4EPKMTP53 | |
| SCHEMBL7394243 | 0.81 | GPR119 (0.41) | HRH3GPR119KDM4EPKMTP53 | |
| SCHEMBL7360610 | 0.80 | GPR119 (0.51) | GPR119TP53LMNAALDH1A1 | |
| SCHEMBL7392102 | 0.79 | GPR119 (0.43) | GPR119KDM4EPKMTP53LMNA | |
| SCHEMBL7394493 | 0.78 | TP53 (0.42) | GPR119KDM4EPKMTP53LMNA | |
| SCHEMBL7481273 | 0.77 | GPR119 (0.41) | GPR119KDM4EPKMTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | claimed |
| WO-1995024405-A1 | IMIDAZOLIDIN-2-ONES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-09-14 | — | — | WO | disclosed |