Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389941 | 0.86 | S1PR1 (0.43) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7484914 | 0.85 | GPR119 (0.42) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7391404 | 0.85 | GPR119 (0.41) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7389887 | 0.84 | HRH3 (0.41) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7360610 | 0.81 | GPR119 (0.51) | GPR119ALDH1A1LMNATP53 | |
| SCHEMBL7393944 | 0.81 | GPR119 (0.41) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7358096 | 0.81 | HRH3 (0.41) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7392102 | 0.80 | GPR119 (0.43) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7394493 | 0.79 | TP53 (0.42) | GPR119KDM4EPKMALDH1A1LMNA | |
| SCHEMBL7481273 | 0.79 | GPR119 (0.41) | GPR119KDM4EPKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |