Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484914 | 0.95 | GPR119 (0.42) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7394243 | 0.86 | GPR119 (0.41) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7355976 | 0.86 | GPR119 (0.42) | GPR119KDM4EPKMALDH1A1FAAH | |
| SCHEMBL7385979 | 0.86 | GPR119 (0.42) | GPR119TP53 | |
| SCHEMBL7481273 | 0.86 | GPR119 (0.41) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7391404 | 0.86 | GPR119 (0.41) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7358096 | 0.85 | HRH3 (0.41) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7389887 | 0.85 | HRH3 (0.41) | GPR119TP53KDM4EPKMALDH1A1 | |
| SCHEMBL7394018 | 0.85 | GPR119 (0.41) | GPR119TP53 | |
| Hydrochloric Acid SCHEMBL7390433 | 0.83 | S1PR1 (0.45) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |