Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 11/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971324 | 0.85 | HTR4 (0.60) | HTR4ACHEDRD2DRD4 | |
| SCHEMBL8970802 | 0.83 | HTR4 (0.61) | HTR4ACHEDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8971667 | 0.82 | HTR4 (0.60) | HTR4ACHEDRD2DRD4 | |
| SCHEMBL8971342 | 0.81 | HTR4 (0.63) | HTR4ACHEDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8970748 | 0.81 | HTR4 (0.62) | HTR4ACHEDRD2DRD4 | |
| SCHEMBL3230370 | 0.80 | HTR4 (0.64) | HTR4ACHEDRD2DRD4HTR3A | |
| Hydrochloric Acid SCHEMBL8971374 | 0.80 | DRD2 (0.52) | HTR4ACHEDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8971647 | 0.80 | DRD2 (0.52) | HTR4ACHEDRD2DRD4 | |
| SCHEMBL7254103 | 0.80 | HTR4 (0.42) | HTR4ACHEDRD2DRD4HTR3A | |
| Hydrochloric Acid SCHEMBL8973729 | 0.79 | HTR4 (0.63) | HTR4ACHEDRD2DRD4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-A1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | disclosed |