Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70894 | 0.88 | PIK3CA (0.46) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL72046 | 0.85 | PTGDR2 (0.51) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL5708317 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL72217 | 0.79 | MAPT (0.41) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL5161089 | 0.73 | HDAC3 (0.51) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL73096 | 0.72 | PTGDR2 (0.52) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL91757 | 0.71 | HDAC3 (0.52) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL91763 | 0.71 | RAB9A (0.64) | SMN1; SMN2TP53RAB9AMEN1MAPT | |
| SCHEMBL8787255 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2TP53MEN1MAPTKMT2A | |
| SCHEMBL9494725 | 0.70 | TSHR (0.58) | SMN1; SMN2TP53RAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |