Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357812 | 0.85 | MAPT (0.38) | GAAPOLBNPSR1MAPTKDM4E | |
| SCHEMBL24147672 | 0.74 | ALDH1A1 (0.38) | GAAPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL27431550 | 0.67 | PSEN1 (0.38) | POLBKDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL17830787 | 0.66 | DAO (0.48) | POLBNPSR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7957934 | 0.65 | F10 (0.53) | GAANPSR1MAPTKDM4EALDH1A1 | |
| SCHEMBL14984829 | 0.64 | ALDH1A1 (0.44) | NPSR1MAPTALDH1A1HPGD | |
| SCHEMBL31520609 | 0.64 | KDM4E (0.43) | GAAMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL20436342 | 0.63 | HTR2A (0.45) | MAPTTNF | |
| SCHEMBL11327841 | 0.63 | HPGD (0.58) | GAAPOLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL7358239 | 0.63 | HPGD (0.51) | GAANPSR1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037343-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
| WO-1996019223-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |