Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27343262 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL7957934 | 0.80 | F10 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27354976 | 0.79 | TNF (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19013560 | 0.69 | NR1H2 (0.43) | L3MBTL1SLC9A1 | |
| SCHEMBL24147672 | 0.69 | ALDH1A1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19013496 | 0.68 | NR1H2 (0.42) | L3MBTL1SLC9A1 | |
| SCHEMBL29631856 | 0.68 | NR1H2 (0.42) | L3MBTL1SLC9A1 | |
| SCHEMBL7358822 | 0.67 | GAA (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Ethoxycarbonyl Group SCHEMBL27490855 | 0.67 | CREBBP (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20097079 | 0.66 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1SLC9A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058969-C | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 2000-11-29 | — | — | CN | disclosed |