Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 18/20 | 0.50 |
| ▸ | PLAT | P00750 | 15/20 | 0.50 |
| ▸ | F2 | P00734 | 14/20 | 0.50 |
| ▸ | PLG | P00747 | 14/20 | 0.50 |
| ▸ | F10 | P00742 | 8/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.46 |
| ▸ | KLK1 | P06870 | 5/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344367 | 0.90 | PLAU (0.48) | PLAUPLATF2PLGF10 | |
| SCHEMBL7853605 | 0.87 | PLAU (0.48) | PLAUPLATF2PLGF10 | |
| SCHEMBL7854268 | 0.83 | NPC1 (0.46) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL7852369 | 0.83 | SORT1 (0.46) | — | |
| SCHEMBL7853919 | 0.82 | PLAU (0.66) | PLAUPLATF2PLGF10 | |
| SCHEMBL7854754 | 0.82 | PLAU (0.64) | PLAUPLATF2PLGF10 | |
| SCHEMBL7856137 | 0.78 | PLAU (0.67) | PLAUPLATF2PLGKLKB1 | |
| SCHEMBL7855528 | 0.77 | PLAU (0.49) | PLAUPLATF2PLGKLKB1 | |
| Trifluoroacetic Acid SCHEMBL7359134 | 0.77 | PLAU (0.66) | PLAUPLATF2PLGF10 | |
| SCHEMBL7336455 | 0.74 | PLAU (0.78) | PLAUPLATF2PLGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258822-B1 | ENZYME INHIBITORS OF NAPHTHALENE AMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-07-10 | — | — | US | disclosed |