Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 12/20 | 0.49 |
| ▸ | F2 | P00734 | 6/20 | 0.49 |
| ▸ | PLG | P00747 | 6/20 | 0.49 |
| ▸ | PLAT | P00750 | 6/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.49 |
| ▸ | KLK1 | P06870 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853919 | 0.88 | PLAU (0.66) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7856137 | 0.87 | PLAU (0.67) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7854754 | 0.84 | PLAU (0.64) | PLAUF2PLGPLATPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7358911 | 0.84 | PLAU (0.62) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7336652 | 0.83 | PLAU (0.70) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7344367 | 0.82 | PLAU (0.48) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7853605 | 0.81 | PLAU (0.48) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7359141 | 0.77 | PLAU (0.50) | PLAUF2PLGPLATPRSS1 | |
| SCHEMBL7854268 | 0.74 | NPC1 (0.46) | PLAUF2PLGPRSS1KLKB1 | |
| SCHEMBL7852369 | 0.74 | SORT1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | PLAU 2/4885F2 38/4885PLG 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.