Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790582 | 0.84 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19ALDH1A1MAPK1MEN1 | |
| SCHEMBL8790127 | 0.84 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19ALDH1A1MAPK1MEN1 | |
| SCHEMBL8791458 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NOTUMNPC1RAB9A | |
| SCHEMBL10853040 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2CYP2C19NOTUMNPC1RAB9A | |
| SCHEMBL22193270 | 0.73 | LTA4H (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL4143101 | 0.72 | ALDH1A1 (0.59) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL6627044 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AALDH1A1 | |
| SCHEMBL7359190 | 0.71 | TMEM97 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AALDH1A1 | |
| SCHEMBL7363294 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL7363296 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |