Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608071 | 0.84 | HSD17B10 (0.44) | HSD17B10ACHEBCHEITGB3ITGA2B | |
| SCHEMBL18173237 | 0.83 | HSD17B10 (0.47) | HSD17B10ITGB3ITGA2B | |
| SCHEMBL31245833 | 0.81 | GAA (0.52) | HSD17B10 | |
| SCHEMBL24754066 | 0.79 | MAPT (0.47) | HSD17B10 | |
| SCHEMBL14970780 | 0.78 | HSD17B10 (0.39) | HSD17B10ITGB3ITGA2B | |
| SCHEMBL6069474 | 0.78 | PKM (0.47) | ITGB3ITGA2B | |
| SCHEMBL3865449 | 0.78 | ACHE (0.35) | ACHEMMP3MMP8TYMPAKR1C3 | |
| SCHEMBL14609561 | 0.78 | HSD17B10 (0.45) | HSD17B10ITGB3ITGA2B | |
| SCHEMBL15210909 | 0.78 | PLG (0.47) | HSD17B10ITGB3ITGA2B | |
| SCHEMBL6889226 | 0.78 | HSD17B10 (0.45) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059498-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |