Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26349586 | 0.86 | PAOX (0.37) | HSD17B10BCHEACHEITGB3ITGA2B | |
| SCHEMBL7359289 | 0.84 | HSD17B10 (0.44) | HSD17B10BCHEACHEITGB3ITGA2B | |
| SCHEMBL11155988 | 0.84 | GLA (0.50) | BCHEACHEITGB3ITGA2BLTA4H | |
| SCHEMBL7062260 | 0.83 | SMN1; SMN2 (0.42) | BCHEACHEITGB3ITGA2BLTA4H | |
| SCHEMBL18930342 | 0.82 | HSD11B1 (0.54) | BCHEACHEITGB3ITGA2BLTA4H | |
| SCHEMBL30312994 | 0.80 | BCHE (0.36) | HSD17B10BCHEACHEHTTHSD11B1 | |
| SCHEMBL24709214 | 0.80 | HTR4 (0.40) | BCHEACHEITGB3ITGA2BLTA4H | |
| SCHEMBL7060631 | 0.80 | GSK3B (0.39) | BCHEACHELTA4HHSD11B1 | |
| SCHEMBL20366141 | 0.79 | PRMT3 (0.46) | BCHEACHEITGB3ITGA2BLTA4H | |
| SCHEMBL24754066 | 0.79 | MAPT (0.47) | HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637318-B1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5686564-A | Peptide derivatives corresponding to the carboxy terminal sequence of hirudin | NOVARTIS CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0637318-A1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | Novartis AG (CH) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993022344-A1 | PEPTIDE DERIVATIVES CORRESPONDING TO THE CARBOXY TERMINAL SEQUENCE OF HIRUDIN | CIBA-GEIGY AG (CH) | 1993-11-11 | — | — | WO | disclosed |