Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7357103 | 0.89 | HTR1A (0.47) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| Hydrochloric Acid SCHEMBL7359064 | 0.84 | SIGMAR1 (0.43) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| SCHEMBL7354508 | 0.84 | SIGMAR1 (0.42) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| SCHEMBL7386018 | 0.84 | SIGMAR1 (0.42) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| SCHEMBL7360005 | 0.83 | HTR1A (0.45) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| SCHEMBL7360074 | 0.83 | SIGMAR1 (0.42) | HTR1ADRD4SIGMAR1PARP1 | |
| SCHEMBL7424139 | 0.83 | SIGMAR1 (0.42) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| SCHEMBL7355240 | 0.83 | HTR1A (0.44) | HTR1ADRD4SIGMAR1PARP1HTR7 | |
| Hydrochloric Acid SCHEMBL7350285 | 0.82 | SIGMAR1 (0.41) | HTR1ADRD4SIGMAR1PARP1DRD2 | |
| SCHEMBL7354368 | 0.81 | HTR1A (0.40) | HTR1ADRD4SIGMAR1PARP1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |