Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360005 | 0.86 | HTR1A (0.45) | HTR1ADRD3DRD2KDM4EPARP1 | |
| SCHEMBL7354368 | 0.84 | HTR1A (0.40) | HTR1ADRD2KDM4EALDH1A1PARP1 | |
| SCHEMBL7359345 | 0.83 | HTR1A (0.47) | HTR1ADRD2PARP1SIGMAR1DRD4 | |
| Hydrochloric Acid SCHEMBL7357103 | 0.83 | HTR1A (0.47) | HTR1ADRD2KDM4EPARP1SIGMAR1 | |
| SCHEMBL7353007 | 0.82 | TRPV4 (0.45) | HTR1AKDM4EALDH1A1MAPTPARP1 | |
| SCHEMBL7358512 | 0.82 | TRPV4 (0.45) | HTR1ADRD3DRD2KDM4EALDH1A1 | |
| SCHEMBL7359027 | 0.82 | SIGMAR1 (0.45) | HTR1ADRD3DRD2KDM4EPARP1 | |
| Hydrochloric Acid SCHEMBL7359064 | 0.82 | SIGMAR1 (0.43) | HTR1ADRD2KDM4EPARP1SIGMAR1 | |
| SCHEMBL7358547 | 0.82 | TSHR (0.39) | HTR1ADRD3KDM4EALDH1A1MAPT | |
| SCHEMBL7360045 | 0.82 | MAPT (0.52) | HTR1ADRD3KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |