Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356464 | 0.93 | F10 (0.43) | F10 | |
| SCHEMBL7372751 | 0.90 | KCNMA1 (0.46) | — | |
| SCHEMBL7360406 | 0.82 | F10 (0.48) | F10KLKB1KCNH2 | |
| SCHEMBL6106814 | 0.78 | F10 (0.48) | F10KLKB1KCNH2 | |
| SCHEMBL7358443 | 0.77 | POLB (0.46) | F10 | |
| SCHEMBL7357718 | 0.76 | F10 (0.45) | F10 | |
| SCHEMBL7359372 | 0.74 | F10 (0.49) | F10KLKB1KCNH2 | |
| SCHEMBL6106818 | 0.74 | F10 (0.58) | F10KLKB1 | |
| SCHEMBL6109873 | 0.73 | NR3C1 (0.49) | F10KLKB1KCNH2 | |
| SCHEMBL7364617 | 0.72 | NPC1 (0.46) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |